Hodgkin's lymphoma
| Autor: | David C. Linch, Lynny Yung |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
Oncology medicine.medical_specialty medicine.medical_treatment Disease Risk Factors immune system diseases hemic and lymphatic diseases Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Combined Modality Therapy business.industry Combination chemotherapy General Medicine Middle Aged Prognosis medicine.disease Hodgkin's lymphoma Hodgkin Disease Lymphoma Surgery Natural history Radiation therapy Localized disease Female business |
| Zdroj: | Postgraduate Haematology, Fifth Edition |
| ISSN: | 0140-6736 |
| DOI: | 10.1016/s0140-6736(03)12777-8 |
| Popis: | Hodgkin's lymphoma was first described in 1832, but the nature of the pathognomic Reed-Sternberg cell, on which diagnosis of the disease is based, has only been elucidated in the past few years. Radiotherapy has been used to treat localised disease since the 1940s, and in the 1960s, effective combination chemotherapy regimens were introduced for anatomically advanced disease. The past three decades have witnessed continued improvement in outcome to such an extent that Hodgkin's lymphoma is now one of the most curable of all non-cutaneous malignancies. With improved survival and extended follow-up, relevance of treatment-induced late effects has become apparent, and modern therapeutic strategies must fully account for these effects. We review the pathology of Hodgkin's lymphoma, and its clinical presentation, investigation, present management, and natural history, including late effects of treatment. |
| Databáze: | OpenAIRE |
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