UV Spectrophotometric Estimation of Acipimox inBulk and Capsule Dosage Form

Autor:	R. Kalaichelvi, B. Thangabalan, A. Elphine Prabahar, P. Vijayaraj Kumar
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Acipimox Chromatography Correlation coefficient Chemistry Analytical chemistry Ultra violet General Chemistry Capsule Dosage Form Molar absorptivity Absorbance lcsh:Chemistry Distilled water lcsh:QD1-999 medicine medicine.drug
Zdroj:	E-Journal of Chemistry, Vol 6, Iss 4, Pp 1117-1120 (2009)
ISSN:	2090-9810 0973-4945
Popis:	A new simple, rapid, accurate, sensitive and precise spectrophotometric method in ultra violet region has been developed for determination of acipimox (ACX) in bulk and capsule dosage form. Acipimox exhibited maximum absorbance at 231 nm with apparent molar absorptivity of 1.5104 × 104in distilled water. Beer’s law was found to be obeyed in the concentration range 1-10 μg mL-1. Correlation coefficient was found to be 0.9998. The developed method was validated respect to linearity, precision, accuracy. The proposed method is useful for the routine estimation of ACX in bulk and capsule dosage form.
Databáze:	OpenAIRE
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