Cosmetic and Skincare Benefits of Cultivated Mycelia from the Chinese Caterpillar Mushroom, Ophiocordyceps sinensis (Ascomycetes)
| Autor: | Ang Xin Song, Ka Chai Siu, Jianyong Wu, Xue Qin Wei, Wai Yin Cheng |
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| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine Ethyl acetate Ophiocordyceps sinensis Cosmetics Epigallocatechin gallate 01 natural sciences Applied Microbiology and Biotechnology 03 medical and health sciences chemistry.chemical_compound 010608 biotechnology Drug Discovery Collagenases Enzyme Inhibitors Mycelium Pharmacology Cordyceps Mushroom biology Traditional medicine Pancreatic Elastase Monophenol Monooxygenase Plant Extracts Arbutin biology.organism_classification 030104 developmental biology chemistry Cosmeceutical |
| Zdroj: | International journal of medicinal mushrooms. 20(7) |
| ISSN: | 1940-4344 |
| Popis: | Mushrooms are potential sources of novel natural cosmeceutical ingredients. This study was conducted to evaluate the cosmetic (skincare) benefits of the valuable medicinal species Ophiocordyceps sinensis (=Cordyceps sinensis). The mycelial extracts of 2 O. sinensis strains, Cs-HK1 and Cs-4, prepared sequentially with ethyl acetate, ethanol, and hot water were tested with in vitro assays for tyrosinase-, collagenase-, and elastase-inhibitory activity. The ethyl acetate extracts of both fungal strains showed potent antityrosinase and antielastase activity, with low half-maximal inhibitory concentrations (0.14-0.47 mg/mL) comparable to those of the respective reference compounds (arbutin and epigallocatechin gallate). All mycelial extracts exhibited moderate or significant anticollagenase activity; most extracts showed a significant photoprotective effect with a sun protection factor up to 25. The results from this study show the potential use of O. sinensis as a source of cosmetic ingredients for skincare applications. |
| Databáze: | OpenAIRE |
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