| Autor: |
Abhishek Goyal, Yogesh Niwariya, Neeraj Pawar, Alkesh Khurana, Poonam Chaudhary |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Recent advances in anti-infective drug discovery. |
| ISSN: |
2772-4352 |
| Popis: |
Introduction: COVID19 causes significant pulmonary microthrombi in some individuals, which can lead to ARDS and death. Thrombolysis could be an effective approach in some patients with severe ARDS. We describe our experience with usage of thrombolytic agents in COVID19 critically ill patients, who were in worsening respiratory failure. Methodology: Retrospective chart analysis was done in patients who were thrombolysed between May 2020- Sept 2020. Analysis was done to find out factors associated with improvement in oxygenation and survival. Results: Twenty seven patients with severe ARDS [all had respiratory rate >30, FiO2 >0.6(on NIV/HFNC) and PiO2/FiO2 ratio Conclusion: In this unprecedented pandemic with high mortality rates, efficacy of early thrombolysis needs to be further explored in randomised controlled trials. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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