Computer analysis of cardiovascular changes during sleep-wake cycle in Sprague-Dawley rats
| Autor: | J. Lacombe, J. M. Meunier, Anne Nosjean, Raul Laguzzi |
|---|---|
| Přispěvatelé: | Neuropsychopharmacologie moléculaire, cellulaire et fonctionnelle, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 1988 |
| Předmět: |
Male
Periodicity MESH: Periodicity Physiology [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology MESH: Monitoring Physiologic Blood Pressure MESH: Signal Processing Computer-Assisted 0302 clinical medicine Heart Rate Reference Values MESH: Animals MESH: Heart Rate Slow-wave sleep 0303 health sciences education.field_of_study CATS [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior MESH: Reference Values [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences Signal Processing Computer-Assisted MESH: Blood Pressure MESH: Rats Inbred Strains Wakefulness Cardiology and Cardiovascular Medicine medicine.medical_specialty MESH: Sleep MESH: Rats Population Rapid eye movement sleep Biology MESH: Cardiovascular Physiological Phenomena Cardiovascular Physiological Phenomena MESH: Electromyography 03 medical and health sciences Physiology (medical) Internal medicine Heart rate medicine Animals Circadian rhythm education Monitoring Physiologic 030304 developmental biology Electromyography Rats Inbred Strains MESH: Male Rats Surgery MESH: Wakefulness Endocrinology Blood pressure Sleep 030217 neurology & neurosurgery |
| Zdroj: | AJP-Heart and Circulatory Physiology AJP-Heart and Circulatory Physiology, American Physiological Society, 1988, 254 (2), pp.H217-H222. ⟨10.1152/ajpheart.1988.254.2.H217⟩ AJP-Heart and Circulatory Physiology, 1988, 254 (2), pp.H217-H222. ⟨10.1152/ajpheart.1988.254.2.H217⟩ |
| ISSN: | 0363-6135 1522-1539 |
| Popis: | International audience; Blood pressure (BP) and heart rate (HR) were recorded in seven Sprague-Dawley rats during a total of 491 normal sleep-wake cycles with the use of a computer-assisted method developed for this study. Significant changes of BP, HR, and BP variability (BPV) were found between the three states within the cycle, i.e., wakefulness (W), slow-wave sleep (SWS), and paradoxical sleep (PS). The highest BP, BPV, and HR values were found during W. Then all cardiovascular (CV) variables fell during SWS, whereas BP and BPV rose again during PS. The fall of BPV observed during SWS was the most important CV change observed within the cycle. These state-dependent CV changes suggest that, in the rat, circulation during the sleep-wake cycle is controlled by the same central factors that operate in cats. In addition, significant BP and HR modifications between different cycles have been found. On the other hand, BP and HR differences between animals were also observed. The latter differences were found to be stable across the states, but no significant relation was found between BP and HR within any state. Thus the present data also suggest that BP and HR measurements are influenced not only by state-dependent factors but also by at least three different factors that are each independent of the state: one leads to BP and HR values that are influenced by the cycle the animal is in and the other two influence, respectively, the ranking of the individual's BP and HR levels within the population. |
| Databáze: | OpenAIRE |
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