Risk Factors of Peptic Ulcer in 4943 Inpatients
| Autor: | Alessandro Lechi, Giorgio Talamini, Marina Tommasi, Italo Vantini, Giovanna Scroccaro, Benedetta Pajusco, Anna Fratucello, Valeria Amadei |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Peptic Ulcer medicine.medical_specialty Time Factors medicine.drug_class Spirillaceae Proton-pump inhibitor Gastroenterology Endoscopy Gastrointestinal Helicobacter Infections Risk Factors Internal medicine Epidemiology medicine Humans Stomach Ulcer Risk factor Medical prescription Retrospective Studies biology business.industry Incidence Incidence (epidemiology) Anti-Inflammatory Agents Non-Steroidal Smoking Retrospective cohort study Middle Aged Helicobacter pylori Prognosis biology.organism_classification digestive system diseases Italy Duodenal Ulcer Female business Follow-Up Studies |
| Zdroj: | Journal of Clinical Gastroenterology. 42:373-380 |
| ISSN: | 0192-0790 |
| DOI: | 10.1097/mcg.0b013e3180318ac5 |
| Popis: | Background: Over the past few years, major changes have taken place in the treatment of gastroduodenal peptic ulcer. Aim: To evaluate risk factors associated with the incidence of peptic ulcer in inpatients. Methods: From 2001 to 2004, the number of prescriptions of H 2 -antagonists and proton pump inhibitors (PPIs) in each department of Verona University Hospital was monitored. Over the same period we prospectively recorded the number of upper endoscopies per department for inpatients with a diagnosis of peptic ulcer. Results: We analyzed 4943 inpatients. A significantly decreasing trend in H 2 -antagonist prescriptions (r = - 0,88; P < 0.001) and an increasing trend in PPI prescriptions (r = 0.97; P < 0.001) were observed. The endoscopic incidence of duodenal ulcers decreased linearly from 2001 to 2004 as follows: 6.5% (94/1439) in 2001, 5.6% (82/1473) in 2002, 4.5% (63/1411) in 2003, and 3.1% (22/ 702) (P |
| Databáze: | OpenAIRE |
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