Collagen Matrix With Mucoperiosteum Graft as an Effective Fatless Flapless Reconstruction After Endoscopic Pituitary Adenoma Resection
| Autor: | Ricardo L. Carrau, Juan M. Revuelta Barbero, Alexandre B. Todeschini, Bradley A. Otto, Mostafa Shahein, Guillermo Maza, Daniel M. Prevedello, Alaa S. Montaser |
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| Rok vydání: | 2020 |
| Předmět: |
Adenoma
Leak medicine.medical_specialty 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Pituitary adenoma medicine Humans Pituitary Neoplasms Retrospective Studies Base of skull Cerebrospinal fluid leak medicine.diagnostic_test business.industry medicine.disease Surgery Endoscopy 030220 oncology & carcinogenesis Mucoperiosteum Collagen Neurology (clinical) Neoplasm Recurrence Local business Body mass index 030217 neurology & neurosurgery |
| Zdroj: | Operative Neurosurgery. 19:E573-E580 |
| ISSN: | 2332-4260 2332-4252 |
| DOI: | 10.1093/ons/opaa212 |
| Popis: | BACKGROUND Proper skull base reconstruction after endoscopic endonasal pituitary surgery is of great importance to decrease the rate of complications. OBJECTIVE To assess the safety and efficacy of reconstruction with materials other than fat graft and naso-septal flaps (NSF) to avoid their associated morbidities. METHODS The authors' institutional database for patients who underwent endoscopic endonasal approach for pituitary adenoma was reviewed. Exclusion criteria included recurrence, postradiation therapy, and reconstruction by fat graft or NSF. They were divided into group A, where collagen matrix (CM) (DuraGen® Plus Matrix, Integra LifeSciences Corporation, Plainsboro, New Jersey) alone was used; group B, where CM and simple mucoperiosteum graft were used and group C, which included cases without CM utilization. RESULTS The study included 252 patients. No age, gender, or body mass index statistically significant difference between groups. Group B included the largest tumor size (23.0 mm) in comparison to groups A (18.0 mm) and C (13.0 mm). Suprasellar extension was more frequently present (49.4%) in comparison to groups A (29.8%, P = .001) and C (21.2%, P |
| Databáze: | OpenAIRE |
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