Binding studies of an arabinogalactan-protein from Echinacea purpurea to leucocytes
| Autor: | D. Barz, S. Thude, Wolfgang Blaschek, Birgit Classen, H. Thude |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Cell
Pharmaceutical Science Echinacea Microbiology Flow cytometry Echinacea (animal) Mucoproteins Drug Discovery medicine Leukocytes Humans Receptor Arabinogalactan protein Plant Proteins Pharmacology biology medicine.diagnostic_test Plant Components Aerial biology.organism_classification Flow Cytometry medicine.anatomical_structure Complementary and alternative medicine Biochemistry biology.protein Molecular Medicine Antibody CD8 Phytotherapy Protein Binding |
| Zdroj: | Phytomedicine : international journal of phytotherapy and phytopharmacology. 13(6) |
| ISSN: | 0944-7113 |
| Popis: | Flow cytometric investigations show binding of an isolated arabinogalactan-protein (AGP) from pressed juice of the aerial parts of Echinacea purpurea to the cell surface of human leucocytes. AGP demonstrates binding to lymphocytes, monocytes and granulocytes of different donors (n=8). Competition assays with two antibodies, directed against CD4 and CD8, revealed no interaction of AGP with these receptors, leading to the conclusion that binding of AGP to leucocytes is mediated via other structures. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect