Recent progress in materials development and biological properties of GTR membranes for periodontal regeneration
| Autor: | Bushra Anees Palvasha, Bushra Bilal, Aysha Mohyuddin, Nawshad Muhammad, Syed Ali Raza Naqvi, Zufiqar Ali, Sadaf ul Hassan, Sohail Nadeem, Muhammad Shahid Nazir |
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| Rok vydání: | 2021 |
| Předmět: |
Calcium Phosphates
Periodontium Silver Metal Nanoparticles Dentistry Biocompatible Materials Biochemistry Anti-Infective Agents Biological property Drug Discovery medicine Humans Periodontal fiber Cementum Dental alveolus Pharmacology Periodontitis Drug Carriers business.industry Chemistry Regeneration (biology) Organic Chemistry Membranes Artificial medicine.disease medicine.anatomical_structure Membrane Guided Tissue Regeneration Periodontal Molecular Medicine business |
| Zdroj: | Chemical Biology & Drug Design. 98:1007-1024 |
| ISSN: | 1747-0285 1747-0277 |
| DOI: | 10.1111/cbdd.13959 |
| Popis: | Chronic periodontal is a very common infection that instigates the destruction of oral tissue, and for its treatment, it is necessary to minimize the infection and the defects regeneration. Periodontium consists of four types of tissues: (a) cementum, (b) periodontal ligament, (c) gingiva, and 4) alveolar bone. In separated cavities, regenerative process also allows various cell proliferations. Guided tissue regeneration (GTR) is a potential procedure that favors periodontal regrowth; however, some limitations (such as ineffective hemostatic property, poor mechanical property, and improper biodegradation) are also associated with it. This review mainly emphasizes on the following areas: (a) a summarized overview of the periodontium and its immunological situations, (b) recently utilized treatments for regeneration of distinctive periodontal tissues; (c) an overview of GTR membranes available commercially, and the latest developments on the characterization and processing of GTR membrane material; and 4) the function of the different non-polymeric/polymeric materials, which are acting as drug carriers, antibacterial agents, nanoparticles, and periodontal barrier membranes to prevent periodontal inflammation and to improve the strength of the GTR membrane. |
| Databáze: | OpenAIRE |
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