The Correlations of Clinical and Biochemical Indices of Vitamin D with Erectile Dysfunction
| Autor: | Emil Ceban, Ion Dumbrăveanu, Iurie Arian, Pavel Banov |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty 030209 endocrinology & metabolism vitamin D Disease 030226 pharmacology & pharmacy vitamin D deficiency endothelial dysfunction Pathogenesis 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Erectile Dysfunction Internal medicine Surveys and Questionnaires Vitamin D and neurology Medicine Humans Endothelial dysfunction Aged Cholesterol business.industry Testosterone (patch) General Medicine Middle Aged medicine.disease Erectile dysfunction Endocrinology chemistry Original Article business Biomarkers |
| Zdroj: | Journal of Medicine and Life |
| ISSN: | 1844-3117 |
| Popis: | Erectile dysfunction is a multifactorial disease; it has been demonstrated that endothelial dysfunction plays an essential role in the pathogenesis of this disease, and Vitamin D deficiency is considered to favor endothelial lesions. Our study, based on a group of 58 patients who have erectile dysfunction and a control group of 26 healthy subjects, tends to confirm that low levels of vitamin D could potentiate the severity of erectile dysfunction, promoting endothelial dysfunction. Statistical analysis using the Pearson’s correlation criteria showed a robust and significant correlation between vitamin D levels and erectile dysfunction severity (ρ=0.752, p Vitamin D level reduction, concomitantly with decreased testosterone and increased cholesterol, contributes to the development and maintenance of erectile dysfunction, more probably through endothelial mechanisms. The assessment of vitamin D values can be used as an independent marker in erectile dysfunction assessment. Thus, one of the diagnostic tests recommended for erectile dysfunction should be the determination of the vitamin D serum level. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|