Serological survey of human immunodeficiency virus (HIV) in Ethiopia
Autor: | Stefano Buttò, Paola Verani, Fausto Titti, Paolo Pasquini, K. Hailu, D. Bekura, Leonardo Sernicola, Giovanni B. Rossi, M. Rapicetta |
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Rok vydání: | 1989 |
Předmět: |
Adult
Male medicine.medical_specialty Hepatitis B virus Population Blotting Western Radioimmunoassay Enzyme-Linked Immunosorbent Assay HIV Antibodies medicine.disease_cause Virus Serology Hepatitis B Antigens Acquired immunodeficiency syndrome (AIDS) Virology Epidemiology Medicine Humans education education.field_of_study Acquired Immunodeficiency Syndrome business.industry AIDS Serodiagnosis Hepatitis B medicine.disease Precipitin Tests Infectious Diseases Cross-Sectional Studies Military Personnel HIV-2 HIV-1 Female Viral disease Ethiopia business |
Zdroj: | Journal of medical virology. 28(1) |
ISSN: | 0146-6615 |
Popis: | To assess the prevalence of human immunodeficiency virus (HIV) infection in Ethiopia a representative sample of the countrys population was screened by the enzyme-linked immunosorbent assay (ELISA) test. As there has been a high endemicity of hepatitis B virus (HBV) in Ethiopia the analysis was performed as part of a national hepatitis B seroepidemiologic study conducted in 1985-86. It included 2 study populations: 1) 5265 military recruits aged 18-30 years from each region of Ethiopia and 2) 300 outpatients (91 males and 209 females) also 18-30 years of age from the Arsi regions Asella Hospital. According to the ELISA test 119 (22%) of the military recruits and 2 (0.6%) of the hospital outpatients were reactive for HIV-1 antibodies. However Western blot analysis confirmed these reactivities in only 4 subjects--all military recruits. There was no association between unconfirmed reactivity (by ELISA) and the presence of HBV markers. On the other hand all 4 sera samples confirmed by Western blot analysis had at least 1 HBV marker suggesting a similar epidemiology for both infections. All 4 HIV-positive men were from remote areas of Ethiopia reported more than 5 sexual partners and had frequent exposure to intramuscular injections. Overall these findings confirm the observation that HIV infection is not widespread in Ethiopias general population at least as of 1986. |
Databáze: | OpenAIRE |
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