Serological survey of human immunodeficiency virus (HIV) in Ethiopia

Autor: Stefano Buttò, Paola Verani, Fausto Titti, Paolo Pasquini, K. Hailu, D. Bekura, Leonardo Sernicola, Giovanni B. Rossi, M. Rapicetta
Rok vydání: 1989
Předmět:
Zdroj: Journal of medical virology. 28(1)
ISSN: 0146-6615
Popis: To assess the prevalence of human immunodeficiency virus (HIV) infection in Ethiopia a representative sample of the countrys population was screened by the enzyme-linked immunosorbent assay (ELISA) test. As there has been a high endemicity of hepatitis B virus (HBV) in Ethiopia the analysis was performed as part of a national hepatitis B seroepidemiologic study conducted in 1985-86. It included 2 study populations: 1) 5265 military recruits aged 18-30 years from each region of Ethiopia and 2) 300 outpatients (91 males and 209 females) also 18-30 years of age from the Arsi regions Asella Hospital. According to the ELISA test 119 (22%) of the military recruits and 2 (0.6%) of the hospital outpatients were reactive for HIV-1 antibodies. However Western blot analysis confirmed these reactivities in only 4 subjects--all military recruits. There was no association between unconfirmed reactivity (by ELISA) and the presence of HBV markers. On the other hand all 4 sera samples confirmed by Western blot analysis had at least 1 HBV marker suggesting a similar epidemiology for both infections. All 4 HIV-positive men were from remote areas of Ethiopia reported more than 5 sexual partners and had frequent exposure to intramuscular injections. Overall these findings confirm the observation that HIV infection is not widespread in Ethiopias general population at least as of 1986.
Databáze: OpenAIRE