Treatment of Uveitis and Outcomes of Glaucoma Drainage Implant Surgery: A Meta-Analysis
| Autor: | Asima Bajwa, Jae K Lee, Meenakshi Chaku, Peter A. Netland |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual Acuity Immunomodulation Uveitis 03 medical and health sciences 0302 clinical medicine Uveitic glaucoma medicine Immunology and Allergy Humans Glaucoma Drainage Implants Intraocular Pressure 030203 arthritis & rheumatology Glaucoma drainage implant business.industry Glaucoma Middle Aged medicine.disease Surgery Ophthalmology Treatment Outcome Meta-analysis Surgery outcome 030221 ophthalmology & optometry Etiology Female business Medical therapy Follow-Up Studies |
| Zdroj: | Ocular immunology and inflammation. 28(5) |
| ISSN: | 1744-5078 |
| Popis: | Purpose We performed a meta-analysis to evaluate the effect of uveitis treatment on glaucoma drainage implant surgical outcomes. Methods We included 16 articles in the meta-analysis. Two groups were defined based on medical therapy of uveitis: Group 1: poorly controlled uveitis, and Group 2: well-controlled uveitis including use of immunomodulatory medications. Results The two groups were similar in comparisons of follow-up time, age, gender, and etiology of uveitis. Meta-analysis demonstrated significantly greater success in Group 2 (95.1%) compared to Group 1 (81.6%) at 1 year after glaucoma drainage implant surgery (P = .001). The final success was significantly greater (P 0.014) in group 2 compared with group 1 (86.1% and 74.3%, respectively). Conclusion Surgical success was significantly higher in uveitic glaucoma patients treated with more intensive immunosuppressive therapy before and after glaucoma drainage implant surgery. The level of control of uveitis perioperatively appears to influence glaucoma drainage implant surgery outcomes. |
| Databáze: | OpenAIRE |
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