Unique optical coherence tomographic features in age-related macular degeneration
| Autor: | Giuseppe Querques, Manuel Paez-Escamilla, Marco Lupidi, Sai Bhakti Mishra, Sumit Randhir Singh, Jay Chhablani |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures Retinal Pigment Epithelium Drusen Cystoid degeneration Macular Degeneration 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Optical coherence tomography Ophthalmology medicine Humans Clinical significance Retinal pigment epithelium medicine.diagnostic_test Choroid business.industry Retinal Macular degeneration medicine.disease eye diseases medicine.anatomical_structure chemistry 030221 ophthalmology & optometry sense organs business Tomography Optical Coherence 030217 neurology & neurosurgery |
| Zdroj: | Survey of Ophthalmology. 65:451-457 |
| ISSN: | 0039-6257 |
| DOI: | 10.1016/j.survophthal.2020.01.001 |
| Popis: | Age-related macular degeneration is a major cause of blindness worldwide characterized by the presence of drusen and leading to retinal pigment epithelium and outer retinal changes in advanced stages. Approximately 10% of eyes with age-related macular degeneration develop neovascular complications and present with retinal or sub-retinal pigment epithelium exudation, hemorrhage, or both. Recent advances in imaging techniques, especially optical coherence tomography (OCT), help in early identification of disease and guide various treatment decisions; however, not all signs are suggestive of ongoing exudation or neovascular activity. Although uncommon, multiple OCT-based signs are reported that may be difficult to appreciate clinically. Prompt identification of these signs such as outer retinal tubulation, cystoid degeneration, or pseudocysts may avoid unnecessary interventions. Moreover, certain OCT-based features involving the choroid, such as prechoridal cleft and choroidal cavern, have also been found in eyes with age-related macular degeneration. We discuss these unique OCT-based signs, their pathogenesis, clinical relevance, and management. |
| Databáze: | OpenAIRE |
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