Jaw metastasis as first presentation of lung adenocarcinoma. A case report
| Autor: | Paulo Valejo Coelho, Cátia Mateus, Patrícia Santos, Pedro Gomes de Oliveira |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Gynecology
medicine.medical_specialty Lung medicine.diagnostic_test business.industry Cancer oral cancer medicine.disease lung adenocarcinoma Metastasis stomatognathic diseases medicine.anatomical_structure Otorhinolaryngology Biopsy Carcinoma medicine Adenocarcinoma Mandibular metastasis Surgery Oral Surgery Differential diagnosis Lung cancer business lung carcinoma |
| Zdroj: | Revista Española de Cirugía Oral y Maxilofacial v.43 n.2 2021 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud Banco de España |
| Popis: | espanolRESUMEN Las metastasis de la cavidad oral son lesiones raras y constituyen el 1 % de las enfermedades orales malignas. El cancer de pulmon es el tumor primario que se disemina con mas frecuencia en los maxilares, sobre todo en hombres, viendose la mandibula mas afectada que la maxila. El caso que presentamos corresponde a una paciente de 64 anos que acudio a nuestro hospital con una tumefaccion del angulo y de la rama ascendente mandibular de 7 meses de evolucion. Inicialmente en el diagnostico diferencial se incluyeron los tumores primarios de la cavidad oral, pero tras el resultado de la biopsia, se identifico un carcinoma de origen desconocido. El estudio de extension puso de manifiesto un adenocarcinoma de pulmon en estadio avanzado. La presencia de metastasis orales es una evidencia de enfermedad diseminada y se asocian a un mal pronostico, por lo cual los tratamientos para estos pacientes suelen ser paliativos. EnglishABSTRACT Metastatic disease of the oral cavity is rare and constitutes 1 % of all oral cavity malignancies. Lung cancer is the most common primary site metastasizing to the jaws, especially in man, and the mandible is more affected than the maxilla. We present the case of a 64 year-old-female patient who was admitted to hospital complaining of pain and swelling located to the left mandibular ascending ramus and angle, with 7 month duration. The first differential diagnosis was between primary malignances of the oral cavity, but the biopsy revealed a carcinoma of unknown origin. Further investigation revealed an advanced stage primary adenocarcinoma of the lung. Oral metastasis are usually evidence of a widespread disease and indicate a poor prognosis. As consequence, the treatment modalities for these patients are palliative in most cases. The clinical case of a 41-year-old male evaluated for a tumor in the attached gingiva with previous periodontal treatment and a history of kidney transplantation is described. Excisional biopsy was performed with a diagnosis of KS, which after completing the study confirmed disseminated iatrogenic-type KS requiring a change in immunosuppressive medication and 6 cycles of chemotherapy treatment with complete response. |
| Databáze: | OpenAIRE |
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