| Autor: |
Nicholas Crombie, Heidi A Doughty, Jonathan R B Bishop, Amisha Desai, Emily F Dixon, James M Hancox, Mike J Herbert, Caroline Leech, Simon J Lewis, Mark R Nash, David N Naumann, Gemma Slinn, Hazel Smith, Iain M Smith, Rebekah K Wale, Alastair Wilson, Natalie Ives, Gavin D Perkins |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| ISSN: |
2352-3026 |
| Popis: |
Background\ud Time to treatment matters in traumatic haemorrhage but the optimal prehospital use of blood in major trauma remains uncertain. We investigated whether use of packed red blood cells (PRBC) and lyophilised plasma (LyoPlas) was superior to use of 0·9% sodium chloride for improving tissue perfusion and reducing mortality in trauma-related haemorrhagic shock.\ud \ud Methods\ud Resuscitation with pre-hospital blood products (RePHILL) is a multicentre, allocation concealed, open-label, parallel group, randomised, controlled, phase 3 trial done in four civilian prehospital critical care services in the UK. Adults (age ≥16 years) with trauma-related haemorrhagic shock and hypotension (defined as systolic blood pressure |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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