Subacute leukoencephalitis caused by CNS infection with human herpesvirus-6 manifesting as acute multiple sclerosis
| Autor: | Konstance K. Knox, Daniel Harrington, Donald R. Carrigan |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Multiple Sclerosis viruses Herpesvirus 6 Human Disease medicine.disease_cause Herpesviridae Central nervous system disease Central Nervous System Diseases medicine Humans biology business.industry Multiple sclerosis virus diseases Herpesviridae Infections biology.organism_classification medicine.disease Immunology Acute Disease Immunohistochemistry Encephalitis Human herpesvirus 6 Female Neurology (clinical) Viral disease business |
| Zdroj: | Neurology. 47(1) |
| ISSN: | 0028-3878 |
| Popis: | Several recent reports have documented the neuroinvasiveness of human herpesvirus-6 (HHV-6) in infants with primary HHV-6 infections, in children and adults with AIDS, in recipients of bone marrow transplants, and in immunologically intact adults and children. CNS infections with HHV-6 can be subacute and are frequently associated with diffuse or multifocal demyelination. We analyzed the CNS tissues of a young woman who died of a demyelinative disease, which was clinically and histopathologically diagnosed as acute multiple sclerosis, for active HHV-6 infection by immunohistochemical staining. The tissues contained a dense and disseminated active HHV-6 infection that was intimately related to the pathologic changes present.NEUROLOGY 1996;47: 145-148 |
| Databáze: | OpenAIRE |
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