Familial abdominal aortic aneurysm: prevalence and implications for screening
| Autor: | S. W. Galloway, B. R. Tulloh, A.J. Tulloh, E. Shaw, K.R. Poskitt, D. C. R. Adams |
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| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Aneurysm Ultrasound screening Risk Factors medicine Prevalence Humans Mass Screening cardiovascular diseases First-degree relatives Aged Ultrasonography Aortic dilatation Aged 80 and over High prevalence business.industry Familial abdominal aortic aneurysm Middle Aged medicine.disease Abdominal aortic aneurysm Surgery England cardiovascular system Feasibility Studies Female Cardiology and Cardiovascular Medicine business Aortic Aneurysm Abdominal |
| Zdroj: | European journal of vascular surgery. 7(6) |
| ISSN: | 0950-821X |
| Popis: | The high prevalence of abdominal aortic aneurysm (AAA) in men over the age of 65 has led to the establishment of ultrasound screening programmes for this group. The apparent familial tendency towards AAA formation suggests that relatives of aneurysm patients may form another subpopulation in whom screening is appropriate. The first degree relatives of 100 consecutive aneurysm patients were identified. Of 110 relatives over 50 years of age, two were known to have had AAA and ultrasound scans were performed on 74, providing information on aortic size for 76 relatives (69%). No further aortic aneurysms (antero-posterior diameteror = 4.0 cm) were found on scanning. However, nine relatives were demonstrated to have aortic dilatation (2.5-3.9 cm). Aortic dilatation was observed in 21% of male first degree relatives over 50 years of age, affecting 27% of sons and 17% of brothers. Only 4% of the sisters and none of the daughters were found to have aortic dilatation. The prevalence of aortic enlargement seems to be sufficiently high amongst male first degree relatives of AAA patients over 50 years of age to justify aortic screening. |
| Databáze: | OpenAIRE |
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