Post-transplant soluble MICA and MICA antibodies predict subsequent heart graft outcome

Autor:	R.M. Blanco-García, M. Rocío Álvarez-López, Beatriz Suarez-Alvarez, Beatriz Díaz-Molina, Antonio López-Vázquez, Carlos López-Larrea, Roberto Díaz-Peña
Rok vydání:	2006
Předmět:	Adult Cytotoxicity Immunologic Graft Rejection Male DNA Complementary medicine.medical_treatment Immunology Enzyme-Linked Immunosorbent Assay Human leukocyte antigen Cell Line Isoantibodies Immune system Humans Immunology and Allergy Medicine Soluble mica Heart graft Retrospective Studies Heart transplantation Transplantation Base Sequence biology business.industry Histocompatibility Antigens Class I Middle Aged Recombinant Proteins stomatognathic diseases Treatment Outcome Solubility Acute Disease biology.protein Heart Transplantation Female Mica Antibody business
Zdroj:	Transplant Immunology. 17:43-46
ISSN:	0966-3274
DOI:	10.1016/j.trim.2006.09.014
Popis:	The objective of this retrospective study was to evaluate the role of MICA in heart graft acceptance. Pre- and post-transplant sera from 31 patients were evaluated for MICA antibodies by cytotoxicity on recombinant cell lines and soluble MICA (sMICA) concentrations by ELISA. The results demonstrated that the patients with post-transplant anti-MICA antibodies were at a high risk for the development of severe acute rejection (AR) (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0cd7ef3f6488eab51d608b30077205 https://doi.org/10.1016/j.trim.2006.09.014 Zobrazit plný text záznamu Full Text from ScienceDirect