First partial characterisation of small ruminant lentiviruses from Greece
| Autor: | M. Koumpati-Artopiou, O. Papadopoulos, M. Papanastasopoulou, I. Vlemmas, Katerina Angelopoulou, K. Karanikolaou, G. Koptopoulos |
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| Rok vydání: | 2005 |
| Předmět: |
Molecular Sequence Data
Sheep Diseases Biology Polymerase Chain Reaction Microbiology Animals Small ruminant Amino Acid Sequence Cloning Molecular Phylogeny chemistry.chemical_classification Goat Diseases Sheep Base Sequence Greece General Veterinary Phylogenetic tree Geographic area Goats Strain (biology) Nucleic acid sequence Sequence Analysis DNA General Medicine Group-specific antigen Genes gag Virology Amino acid chemistry Amino acid composition Lentiviruses Ovine-Caprine DNA Viral Lentivirus Infections Sequence Alignment |
| Zdroj: | Veterinary Microbiology. 109:1-9 |
| ISSN: | 0378-1135 |
| DOI: | 10.1016/j.vetmic.2005.04.025 |
| Popis: | Small ruminant lentivirus (SRLV) infections are widespread in Greece, but SRLVs have never been isolated and characterized. In this study, we present the sequence of a 574-nucleotide (191-amino acid) region of the gag gene of SRLV strains from four sheep and one goat from a single geographic area of Greece. All five sequences appeared to be closely related at both nucleotide (2.1-14.2% variation) and deduced amino acid (1.6-4.2% variation) level. Greek SRLV strains were closer to ovine prototypic strains (average divergence 16.8%) than to the caprine strain CAEV-Co (21% divergence). By amino acid composition, the Greek SRLVs were on the average more than twice as distant from CAEV-Co as from other ovine strains. Phylogenetic analysis suggested that Greek strains segregate into a unique group, separate from, but related to, other ovine prototype sequences. |
| Databáze: | OpenAIRE |
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