Antiherpesvirus drugs: a promising spectrum of new drugs and drug targets

Autor:	Priscilla A. Schaffer, Donald M. Coen
Rok vydání:	2003
Předmět:	Pharmacology Drug media_common.quotation_subject Drug Resistance Microbial Herpesviridae Infections General Medicine Drug resistance Biology Bioinformatics Antiviral Agents Drug Discovery Molecular targets Humans Clinical treatment Herpesviridae Nucleic Acid Synthesis Inhibitors media_common
Zdroj:	Nature Reviews Drug Discovery. 2:278-288
ISSN:	1474-1784 1474-1776
Popis:	In the absence of effective vaccines to control herpesvirus infections, nucleosidic antiviral drugs have been the mainstay of clinical treatment since their development in the late 1970s. However, given the drawbacks of these drugs, including the increasing emergence of drug-resistant clinical isolates, new strategies for treating herpesvirus infections are warranted. A range of promising new drugs with novel molecular targets has been developed, but will they cure latent infections?
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c065ec9bde02b4ab14531b17ebaca30 https://doi.org/10.1038/nrd1065 Zobrazit plný text záznamu Plný text ve formátu PDF