Yeast as a model system for studying lipid homeostasis and function
| Autor: | Aline X.S. Santos, Howard Riezman |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Aging
Genotype Saccharomyces cerevisiae ved/biology.organism_classification_rank.species Biophysics Lipidome Models Biological Biochemistry Sphingolipid Lipid homeostasis Structural Biology Yeasts Genetics Homeostasis Model organism Molecular Biology Caloric Restriction Sterol biology ved/biology Lipid metabolism Cell Biology Lipid Metabolism biology.organism_classification Glycerophospholipid Yeast Cell biology Metabolic pathway ddc:540 Proteome lipids (amino acids peptides and proteins) Function (biology) |
| Zdroj: | FEBS Letters, Vol. 586, No 18 (2012) pp. 2858-2867 |
| ISSN: | 0014-5793 |
| Popis: | Lipids are essential eukaryotic cellular constituents. Lipid metabolism has a strong impact on cell physiology, and despite good progress in this area, many important basic questions remain unanswered concerning the functional diversity of lipid species and on the mechanisms that cells employ to sense and adjust their lipid composition. Combining convenient experimental tractability, a large degree of conservation of metabolic pathways with other eukaryotes and the relative simplicity of its genome, proteome and lipidome, yeast represents the most advantageous model organism for studying lipid homeostasis and function. In this review we will focus on the importance of yeast as a model organism and some of the innovative advantages for the lipid research field. |
| Databáze: | OpenAIRE |
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