Amniotic fluid intercellular adhesion molecule-1 is a marker for Ureaplasma infection in women with preterm labor
| Autor: | Noa Shani-Shrem, Moshe Mazor, Shulamith Horowitz, Sharon Horowitz, Amnon Hadar, Oranit Ytzhaki |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Amniotic fluid Intercellular Adhesion Molecule-1 Mycoplasmataceae Sensitivity and Specificity Ureaplasma Andrology Obstetric Labor Premature Predictive Value of Tests Pregnancy medicine Humans biology business.industry Ureaplasma infection Ureaplasma Infections Osmolar Concentration Obstetrics and Gynecology Adhesion medicine.disease biology.organism_classification Amniotic Fluid Exact test Immunology Mollicutes Female business Biomarkers |
| Zdroj: | American journal of obstetrics and gynecology. 195(6) |
| ISSN: | 1097-6868 |
| Popis: | Objective The objective of the study was to determine the amniotic fluid soluble intercellular adhesion molecule-1 concentrations in women with preterm labor in relation to intra-amniotic infection. Study design Amniotic fluids from 125 women with preterm labor (78 with preterm delivery and 47 with term deliveries) were examined for both soluble intercellular adhesion molecule-1 concentrations and intra-amniotic infection with Ureaplasma species. A χ 2 test, or Fisher's exact test, when appropriate, was used for statistical analysis. Results In the preterm delivery group, 45% (35 of 78) had intra-amniotic infection with Ureaplasma species, compared with 19% (9 of 47) in the term delivery group ( P = .004). In women with intra-amniotic infection, 26% (9 of 38) had soluble intercellular adhesion molecule-1 levels above 1290 ng/ml. Only 2.3% (1 of 43) in the preterm delivery group without intra-amniotic infection attained this diagnostic level ( P = .004). In contrast, there was no significant difference in soluble intercellular adhesion molecule-1 levels between those with or without intra-amniotic infection in the term delivery group. Conclusion Amniotic fluid soluble intercellular adhesion molecule-1 concentrations exceeding 1290 ng/ml can be used as a marker for intra-amniotic infection with Ureaplasma in patients with preterm labor. |
| Databáze: | OpenAIRE |
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