Clinical features and lipid profiles of plaque erosion over lipid-rich plaque versus fibrous plaque in patients with acute coronary syndrome
| Autor: | Teruo Sekimoto, Hiroyoshi Mori, Shinji Koba, Taito Arai, Naoki Matsukawa, Rikuo Sakai, Yuya Yokota, Shunya Sato, Hideaki Tanaka, Ryota Masaki, Yosuke Oishi, Kunihiro Ogura, Ken Arai, Kosuke Nomura, Koshiro Sakai, Hiroaki Tsujita, Seita Kondo, Shigeto Tsukamoto, Hiroshi Suzuki, Toshiro Shinke |
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| Rok vydání: | 2022 |
| Předmět: |
Rupture
Spontaneous Coronary Artery Disease Coronary Angiography Coronary Vessels Fibrosis Lipids Plaque Atherosclerotic Lipoproteins LDL Treatment Outcome Cholesterol Humans Acute Coronary Syndrome Cardiology and Cardiovascular Medicine Creatine Kinase Tomography Optical Coherence Retrospective Studies |
| Zdroj: | Atherosclerosis. 360 |
| ISSN: | 1879-1484 |
| Popis: | Pathological reports have shown that plaque erosion (PE), a common cause of acute coronary syndrome (ACS), can form in both fibrous plaque and lipid-rich plaque (LRP). In plaque rupture (PR), which is the main cause of ACS, the underlying plaque is LRP with a thin fibrous cap. In this study, we aimed to investigate the clinical features and lipid profiles of PE with or without LRP in comparison with those of PR.A total of 166 patients with ACS, who underwent percutaneous coronary intervention using optical coherence tomography (OCT) and met the criteria for PR or PE, were included. LRP was defined as plaque with a maximal lipid arc (180°). Culprit lesions were categorized into PR and PE with/without LRP [PEThe prevalence of PR, PEThe clinical features and lipid profiles are substantially different between PE |
| Databáze: | OpenAIRE |
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