Oral Methylergonovine Maleate for Refractory Migraine and Cluster Headache Prevention
| Autor: | Joel R. Saper, Randolph W. Evans |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Aura Migraine Disorders Administration Oral Cluster Headache Methylergonovine medicine Humans Dosing Methylergonovine Maleate business.industry Cluster headache Analgesics Non-Narcotic medicine.disease Regimen Neurology Migraine Anesthesia Female Neurology (clinical) Headaches medicine.symptom business Dihydroergotamine |
| Zdroj: | Headache: The Journal of Head and Face Pain. 53:378-381 |
| ISSN: | 0017-8748 |
| Popis: | This is a 40-year-old woman with an 18-yearhistory of migraine without aura that has beenchronic for 6 years. She has failed or been intolerantto numerous preventive medications, including topi-ramate and onabotulinum toxin even though she doesnot have medication overuse. She did become head-ache free after a 5-day intravenous regimen of dihy-droergotamine,but then the headaches returned overseveral months to their prior frequency.Questions:Might she respond to preventive treat-ment with methylergonovine?What is the mechanismof action, pharmacokinetics, and dosing? Whatadverse events are associated with use? Is methyler-gonovine effective for cluster headache prevention? |
| Databáze: | OpenAIRE |
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