Ca2+Activated K Channels-New Tools to Induce Cardiac Commitment from Pluripotent Stem Cells in Mice and Men

Autor:	Marianne Stockmann, Tobias M. Boeckers, Stefan Liebau, Stephan Latz, Bernd K. Fleischmann, Anna M. Wobus, Martin Müller, Martin Zenke, Daniela Malan, Anne Wolheim, Götz von Wichert, Sarah-Fee Katz, Cornelia Brunner, Michael Tischendorf, Maria Wartenberg, Leonhard Linta, Alexander Kleger, Qiong Lin
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Cancer Research Potassium Channels Transcription Genetic Cellular differentiation Induced Pluripotent Stem Cells Cyclic Nucleotide-Gated Cation Channels Muscle Proteins Mice Potassium Channels Calcium-Activated 03 medical and health sciences KCNN4 0302 clinical medicine Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Animals Humans Myocytes Cardiac Induced pluripotent stem cell Cell Shape Cells Cultured Embryoid Bodies Ion channel Cell Proliferation 030304 developmental biology K channels 0303 health sciences Myosin Heavy Chains Chemistry Cell Differentiation Cell Biology Antigens Differentiation Myocardial Contraction Potassium channel Cell biology Bone morphogenetic protein 4 Benzimidazoles Stem cell Cardiac Myosins 030217 neurology & neurosurgery
Zdroj:	Stem Cell Reviews and Reports; Vol 8 Stem Cell Reviews and Reports
ISSN:	1558-6804
DOI:	10.1007/s12015-011-9324-9
Popis:	To date, the precise role of ion channels in developmental processes has remained elusive, although it is well accepted that cell differentiation and maturation affect the expression patterns of ion channels [1]. Calcium-activated potassium channels (SKCas) exhibit small (SK1-3, Kcnn1-3) or intermediate (SK4, IK, Kcnn4) unitary conductance for Stem Cell Rev and Rep (2012) 8:720–740 DOI 10.1007/s12015-011-9324-9
Databáze:	OpenAIRE
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