Dynamic cardiomyoplasty: long-term clinical results in patients with dilated cardiomyopathy
| Autor: | Grácia H Thèvenard, João Carlos Leal, Moacir Fernandes de Godoy, Maria Christiane Valéria Braga Braile, Rubens S. Thevenard, Max Schaldach, Domingo Marcolino Braile |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Pulmonary and Respiratory Medicine
Adult Cardiomyopathy Dilated Chagas Cardiomyopathy Male medicine.medical_specialty Heart disease Peripartum cardiomyopathy Adolescent medicine.medical_treatment Hemodynamics Postoperative Complications Internal medicine medicine Humans Cardiomyoplasty Contraindication Aged Heart transplantation business.industry Dilated cardiomyopathy Middle Aged medicine.disease Survival Rate Treatment Outcome Evaluation Studies as Topic Heart failure Ventricular fibrillation Ventricular Fibrillation Cardiology Surgery Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | The Annals of thoracic surgery. 69(5) |
| ISSN: | 0003-4975 |
| Popis: | Background. Dynamic cardiomyoplasty has been considered to be an effective method of surgical treatment of patients with end-stage heart failure, and is an alternative to heart transplantation. Methods. We critically evaluated the long-term course of 52 patients with dilated cardiomyopathy who underwent dynamic cardiomyoplasty and were followed-up for up to 110 months. Results. Dilated cardiomyopathy was due to undetermined cause in 42 patients (80.8%), Chagas disease in 8 (15.4%), viral infection in 1 (1.9%), and peripartum cardiomyopathy in 1 (1.9%). In the nonchagasic group the survival rates were 79.5% ± 6.1%, 67.8% ± 7.1%, 53.7% ± 8.3%, 49.9% ± 8.3%, 14.9% ± 12.2%, and 14.9% ± 12.2%, respectively, at 12, 24, 48, 60, 80 and 110 months of follow-up. In the chagasic patients the survival rates were 37.5% ± 17.1%, 12.5% ± 11.7%, 12.5% ± 11.7% and 0%, respectively, at 12, 24, 48, and 60 months of follow-up, making chagasic cardiomyopathy a possible contraindication for dynamic cardiomyoplasty. Conclusions. There was no correlation between the clinical improvement and hemodynamic data. Ventricular fibrillation was a frequent cause of immediate and late death, suggesting the need for prophylactic use of antiarrhythmic drugs or implantable cardioverter/defibrillators. |
| Databáze: | OpenAIRE |
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