Prevalence and Clinical Correlation of Left Ventricular Systolic Dysfunction in African Americans with Ischemic Stroke
| Autor: | Prafulla P. Mehrotra, Shariff Dunlap, Saravana Devulapalli, Stephen Cockburn, Nakia Wilson, Mohankumar Kurukumbi, Annapurni Jayam-Trouth |
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| Rok vydání: | 2014 |
| Předmět: |
Male
medicine.medical_specialty Logistic regression Brain Ischemia Brain ischemia Ventricular Dysfunction Left Risk Factors Internal medicine Prevalence medicine Humans Stroke Aged Retrospective Studies Ejection fraction business.industry Smoking Rehabilitation Atrial fibrillation Retrospective cohort study Middle Aged medicine.disease Black or African American Ischemic stroke Cardiology Female Surgery Neurology (clinical) Abnormality Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Stroke and Cerebrovascular Diseases. 23:1965-1968 |
| ISSN: | 1052-3057 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2014.01.026 |
| Popis: | Background The goal of the present study was to determine the prevalence of left ventricular systolic dysfunction (LVSD) and associated clinical correlates in African Americans (AA) diagnosed with ischemic stroke (IS). Methods Retrospective chart analysis was done on all diagnosed AA IS patients between January 2010 and March 2012. Patients with atrial fibrillation were excluded. A total of 147 patients were included in the study. Transthoracic 2-dimensional echocardiography was used to assess left ventricular systolic function, and study groups were categorized as normal, mild, moderate, and severely abnormal, based on the ejection fraction (EF). Available imaging studies were analyzed for data collection. Logistic regression and Pearson chi-square tests were performed. Results Normal EF was present in 114 of 147 patients (78%). Mild abnormality was present in 9 of 147 (6%), moderate in 8 of 147 (5%), and severe in 16 of 147 (11%) patients. In patients with mildly reduced EF, smoking was the most common (RF). In patients with moderately and severely reduced EFs, hypertension was the most common RF. History of smoking was commonly found in systolic dysfunction group compared with normal group ( P = .001). Logistic regression analysis revealed that smoking and advanced age were the significant predictors for LVSD. Large-vessel IS were more common in systolic dysfunction group than normal EF group ( P = .017). Conclusions Prevalence of LVSD in AA with IS was 22% in our study. Smoking was a significant modifiable RF associated with systolic dysfunction. A history of smoking and higher age could predict the occurrence of LVSD. There were more large-vessel IS in patients with LVSD. |
| Databáze: | OpenAIRE |
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