Left-right differences in ovarian volume and antral follicle count in 1423 women of reproductive age
| Autor: | Kathrine Birch Petersen, Anne-Sofie Korsholm, Helene Westring Hvidman, Anders Nyboe Andersen, J.G. Bentzen |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Anti-Mullerian Hormone endocrine system medicine.medical_specialty Endocrinology Diabetes and Metabolism Reproductive age 03 medical and health sciences Young Adult 0302 clinical medicine Endocrinology Ovarian Follicle Medicine Humans 030212 general & internal medicine Ovarian reserve Ultrasonography Gynecology 030219 obstetrics & reproductive medicine biology business.industry Ovary Obstetrics and Gynecology Anti-Müllerian hormone Organ Size respiratory system Antral follicle Cross-Sectional Studies biology.protein Female business |
| Zdroj: | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 33(4) |
| ISSN: | 1473-0766 |
| Popis: | The aim of this cross-sectional study was to investigate side differences in antral follicle count (AFC) and ovarian volume in left versus right ovaries in relation to chronological and "biological" age, the latter estimated by anti-Müllerian hormone (AMH) levels. The cohort comprised 1423 women: 1014 fertile and 409 infertile. All were examined by transvaginal sonography and serum AMH. Overall the right ovary contained 8.1% more antral follicles (p = 0.002) and had 10.7% larger volume compared with the left (p 0.001). In all AMH quartiles, the right ovarian volume was larger than the left (p ≤ 0.003). AFC was significantly higher in the right compared to the left ovary in the three upper AMH quartiles (p ≤ 0.005). The findings were similar when stratified in age quartiles. More than half (54.8%) had polycystic ovarian (PCO) morphology in at least one ovary. Of these women, 46.3% (n = 361) had PCO morphology unilateral - most frequently on the right side (27.6%) compared to the left (18.7%, p 0.001). The consistent difference in AFC and ovarian volume found in AMH and age quartiles may be explained by presence of a larger pool of primordial follicles in the right ovary established during fetal life. |
| Databáze: | OpenAIRE |
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