Supplementary Figure 1 from Cyclin E2 Overexpression Is Associated with Endocrine Resistance but not Insensitivity to CDK2 Inhibition in Human Breast Cancer Cells

Autor: Elizabeth A. Musgrove, Cristin G. Print, Robert L. Sutherland, Rob I. Nicholson, Julia M. Gee, Lance D. Miller, Michael A. Black, Christine S. Lee, Jane Barraclough, Andrew Stone, Marijke N. Boersma, Anita Muthukaruppan, Jian Kang, C. Marcelo Sergio, C. Elizabeth Caldon
Rok vydání: 2023
DOI: 10.1158/1535-7163.22496373.v1
Popis: PDF file, 929KB, Supplementary Figure 1: Cyclin E2 association with breast cancer subtype, grade, and outcome. A: Relationship between a second cyclin E2 probeset and breast cancer subtype, or histological grade. Box: upper and lower quartiles; dividing line: median. B: Relative expression of cyclin E1 and a second cyclin E2 probeset in individual tumours in breast cancer subtypes. C: Kaplan-Meier survival analysis of distant metastasis-free survival from ER-positive patients treated with endocrine therapy (n=287) and untreated ER-negative patients (n=106), using a 70% cutoff between high and low expression.
Databáze: OpenAIRE