Impact of Magnification Views on the Characterization of Microcalcifications in Digital Mammography
| Autor: | Klaus-Jürgen Winzer, L. Dimitrijevic, Susanne Diekmann, Alexander Poellinger, Felix Diekmann, U. Kettritz, F. Engelken, Diane M. Renz, Ulrich Bick, E. M. Fallenberg |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Digital mammography Breast imaging Magnification Breast Neoplasms Comorbidity Risk Assessment Germany medicine Humans Mammography Radiology Nuclear Medicine and imaging Aged Observer Variation Receiver operating characteristic medicine.diagnostic_test business.industry Calcinosis Middle Aged Causality Radiographic Image Enhancement Female Radiology Observer variation business |
| Zdroj: | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 186:274-280 |
| ISSN: | 1438-9010 1438-9029 |
| Popis: | Purpose: To evaluate the additional benefit of true geometric (air-gap) magnification views for the characterization of microcalcifications in digital mammography. Materials and Methods: After ethical approval, we retrospectively reviewed patient records to identify 100 patients with suspicious microcalcifications (35 malignant, 65 benign) who had a standard digital mammography and an additional digital magnification view in the same projection within three months. All images were obtained using an amorphous silicon-based full-field digital system (Senographe 2000 D, GE Healthcare, Chalfont St. Giles, UK). Images were independently analyzed by six board-certified radiologists. The probability of malignancy was estimated using first standard contact mammography alone (MG) and then mammography in combination with the magnification view (MG+MAG) using a modified Breast Imaging Reporting and Data System (BI-RADS) classification system and a percentage scale. Results were compared using receiver operating characteristic (ROC) analysis. In addition, readers assessed the subjective visibility of the calcifications. Results: For all six readers combined, the area under the curve (AUC) was 0.664 ± 0.052 for MG and 0.813 ± 0.042 for MG + MAG, resulting in a statistically significant improvement of 0.148 ± 0.120. Each reader had a higher AUC for MG + MAG than MG, with the improvement being statistically significant in four of the six readers. In 76.34 % of the cases, MG + MAG resulted in better visibility of calcifications compared with mammography alone. In 33 % slightly more and in 39 % significantly more calcifications were found. Conclusion: Even in digital mammography with the option of using electronic magnification (zoom) at the viewing workstation, true geometric (air-gap) magnification views remain important for the visibility and correct classification of microcalcifications and for the assessment of their extent. Citation Format: • Fallenberg EM, Dimitrijevic L, Diekmann F et al. Impact of Magnification Views on the Characterization of Microcalcifications in Digital Mammography. Fortschr Rontgenstr 2014; 186: 274 – 280 |
| Databáze: | OpenAIRE |
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