Positive selection along the evolution of primate mitogenomes
| Autor: | Carolina Furtado, Albert N. Menezes, Carlos G. Schrago, Héctor N. Seuánez, Maria Carolina Viana |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Primates
Genetics Mitochondrial DNA Nuclear gene biology Phylogenetic tree Callimico goeldii Cell Biology Callicebus lugens biology.organism_classification Genome Evolution Molecular biology.animal Genome Mitochondrial Animals Humans Molecular Medicine Primate Selection Genetic Molecular Biology Gene Phylogeny |
| Zdroj: | Mitochondrion. 13:846-851 |
| ISSN: | 1567-7249 |
| DOI: | 10.1016/j.mito.2013.06.001 |
| Popis: | The mitochondrial genomes of four neotropical primates, Aotus infulatus, Chiropotes israelita, Callimico goeldii and Callicebus lugens were sequenced and annotated. Phylogenetic reconstructions with mitochondrial genes of other 66 primates showed a similar arrangement to a topology based on nuclear genes. Screening for positive selection identified 15 codons in 7 genes along 9 independent lineages, three with two or more genes and five in internal nodes, ruling out false positive estimates. Mitochondrial genes of the electron transport chain (ETC.) complexes evolved with high substitution rates. A study of nuclear ETC. genes might elucidate whether they co-evolved with their mitochondrial counterparts. |
| Databáze: | OpenAIRE |
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