Comparison of repeatability of swept-source and spectral-domain optical coherence tomography for measuring inner retinal thickness in retinal disease

Autor: Jong Hun Yeom, Heeyoon Cho, Eun Hee Hong, Min Ho Kang, So Jung Ryu, Mincheol Seong, Yong Un Shin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Retinal Ganglion Cells
Eye Diseases
genetic structures
Nerve fiber layer
Diagnostic Radiology
Macular Degeneration
chemistry.chemical_compound
Nerve Fibers
Animal Cells
Medicine and Health Sciences
Macula Lutea
Geriatric Ophthalmology
Tomography
Neurons
Multidisciplinary
medicine.diagnostic_test
Radiology and Imaging
Retinal Degeneration
Statistics
Repeatability
Diabetic retinopathy
Middle Aged
medicine.anatomical_structure
Physical Sciences
Retinal Disorders
Medicine
Female
Anatomy
Cellular Types
Epiretinal membrane
Tomography
Optical Coherence

Research Article
Adult
medicine.medical_specialty
Imaging Techniques
Science
Nerve fiber
Research and Analysis Methods
Retina
Retinal Diseases
Optical coherence tomography
Ocular System
Diagnostic Medicine
Ophthalmology
medicine
Humans
Retinopathy
Aged
Reproducibility
Diabetic Retinopathy
business.industry
Biology and Life Sciences
Retinal
Cell Biology
medicine.disease
eye diseases
Cross-Sectional Studies
chemistry
Geriatrics
Macular Disorders
Cellular Neuroscience
Eyes
sense organs
business
Head
Mathematics
Neuroscience
Zdroj: PLoS ONE, Vol 14, Iss 1, p e0210729 (2019)
PLoS ONE
ISSN: 1932-6203
Popis: PurposeTo compare repeatability between SS-OCT and SD-OCT for measurement of macular, macular retinal nerve fiber (mRNFL), and ganglion cell-inner plexiform layer (GC-IPL) thickness in various retinal diseases.MethodsOne hundred and fourteen eyes of 114 subjects were investigated. Seventy-eight eyes with retinal disease and 36 normal eyes underwent two consecutive measurements of macular, mRNFL, and GC-IPL thickness using SS-OCT and SD-OCT. The data were obtained using the Early Treatment Diabetic Retinopathy Study (ETDRS) protocol. The eyes with retinal diseases were divided into three subgroups according to central macular thickness (CMT) for analysis. The intraclass correlation coefficient (ICC) was calculated to determine the repeatability of OCT device.ResultsIn normal eyes, both OCT devices showed excellent repeatability of macula, mRNFL, and GC-IPL thickness measurements with high ICCs in all ETDRS subfields. In eyes with retinal disease, although SS-OCT showed better repeatability for inner retinal thickness measurements than SD-OCT, the overall ICCs were lower than those in normal eyes. In subgroup analysis, the ICCs in the low CMT group were lower than those in the normal and high CMT groups, particularly when using SD-OCT.ConclusionsBoth OCT devices had comparable repeatability for retinal thickness measurement in normal eyes and eyes with retinal disease. However, the possibility of measurement error should be considered in eyes with a thin and atrophic retina.
Databáze: OpenAIRE
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