HIV cascade of care in Greece: Useful insights from additional stages
| Autor: | Nikolopoulos, Georgios, Vourli, Georgia, Paparizos, Vasilios, Skoutelis, Athanasios, Metallidis, Symeon, Gargalianos, Panagiotis, Papadopoulos, Antonios, Chini, Maria, Sipsas, Nikolaos V., Psychogiou, Mina, Chrysos, Georgios, Sambatakou, Helen, Gogos, Charalambos, Katsarou, Olga, Paraskeva, Dimitra, Dedes, Nikos, Touloumi, Giota, Group, on behalf of the Greek HIV Prevention |
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| Přispěvatelé: | Nikolopoulos, Georgios [0000-0002-3307-0246], Vourli, Georgia [0000-0002-9727-2808], Gargalianos, Panagiotis [0000-0001-7070-8635], Sipsas, Nikolaos V. [0000-0001-6955-3453], Sambatakou, Helen [0000-0001-8904-076X] |
| Rok vydání: | 2018 |
| Předmět: |
RNA viruses
Male 0301 basic medicine Human immunodeficiency virus (HIV) lcsh:Medicine HIV Infections Pathology and Laboratory Medicine medicine.disease_cause Geographical locations Men who have sex with men 0302 clinical medicine Immunodeficiency Viruses Risk Factors Public and Occupational Health 030212 general & internal medicine lcsh:Science education.field_of_study Multidisciplinary Greece HIV diagnosis and management Vaccination and Immunization 3. Good health Europe Anti-Retroviral Agents Medical Microbiology Viral Pathogens Viruses Infectious diseases Female Pathogens Research Article Cohort study medicine.medical_specialty Immunology 030106 microbiology Population Men WHO Have Sex with Men Antiretroviral Therapy Viral diseases Microbiology 03 medical and health sciences Antiviral Therapy Acquired immunodeficiency syndrome (AIDS) Retroviruses medicine Humans Heterosexuals European Union Homosexuality Male Heterosexuality education Microbial Pathogens Medicine and health sciences business.industry Public health Lentivirus lcsh:R Organisms Biology and Life Sciences HIV medicine.disease Diagnostic medicine Clinical trial People and Places HIV-1 Population Groupings lcsh:Q Preventive Medicine business Delivery of Health Care Sexuality Groupings Demography |
| Zdroj: | PLOS ONE PLoS ONE, Vol 13, Iss 11, p e0207355 (2018) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0207355 |
| Popis: | Background Aiming to eliminate HIV infection, UNAIDS has set a global “90-90-90” target by 2020. We sought to construct a 6-stages HIV Cascade of Care (CoC) in Greece, overall and by risk group, to assess risk-group and stage-specific progress in achieving the UNAIDS target. Patients and methods Combining data from the HIV/AIDS surveillance system and a population-based HIV cohort study, the CoC included: i) number of people living with HIV (PLHIV) by end of 2013; ii) proportion of PLHIV ever diagnosed; iii) proportion of diagnosed linked-to-care iv) proportion of linked-to-care ever initiating antiretroviral therapy (ART); v) proportion of treated who retained-in-care vi) proportion of those retained-in-care who were virally suppressed (≤200 copies/mL) at their last visit (01/07/2012-31/12/2013). Results In 2013, 14147 PLHIV were in Greece. Overall, proportions of each stage in the cascade were: 78.4% diagnosed; 86% linked-to-care; 78.5% initiated ART; 86.4% retained-in-care, and 87.1% virally suppressed. Totally, 42.6% of all PLHIV were virally suppressed. The percentage diagnosed was lower among heterosexual men and women (heterosexuals) than in MSM (men who have sex with men) or PWID (people who inject drugs). Most MSM were linked to care (97.2% of diagnosed) while a substantial proportion of PWID were not (80.8% of diagnosed). Once treated, PWID remained in care in similar proportions to MSM. Unlike PWID, a high proportion of the retained in care MSM and heterosexuals achieved viral suppression. Conclusions At the end of 2013, we identified gaps in the HIV CoC in Greece, which differed across risk groups. Targeted interventions are critical in optimizing early diagnosis and timely linkage. A 6-stage CoC, stratified by risk group, can inform strategic public health planning in improving HIV treatment outcomes. |
| Databáze: | OpenAIRE |
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