Changes of platelets, serum lactic dehydrogenase, .GAMMA.-glutamyltranspeptidase, choline esterase and creatine phosphokinase levels in patients with Cushing's syndrome
| Autor: | Tatsuo Sato, Tatsuya Shimada, Yumiko Fujii, Ryoji Hiramatsu, Taisuke Iwaoka, Teruhisa Umeda |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Blood Platelets
medicine.medical_specialty Esterase General Biochemistry Genetics and Molecular Biology Leucyl Aminopeptidase Cushing syndrome chemistry.chemical_compound Internal medicine medicine Cholinesterases Humans Choline Platelet Aspartate Aminotransferases Gamma-glutamyltransferase Creatine Kinase Cushing Syndrome L-Lactate Dehydrogenase biology Platelet Count business.industry Alanine Transaminase gamma-Glutamyltransferase General Medicine Clinical Enzyme Tests Alkaline Phosphatase medicine.disease Endocrinology chemistry Alanine transaminase biology.protein Alkaline phosphatase Creatine kinase business |
| Zdroj: | The Tohoku Journal of Experimental Medicine. 142:195-200 |
| ISSN: | 1349-3329 0040-8727 |
| DOI: | 10.1620/tjem.142.195 |
| Popis: | In order to identify non-endocrine laboratory tests of diagnostic value in Cushing's syndrome, we measured platelet counts and serum myogenic and hepatic enzyme levels in 10 patients with Cushing's syndrome and compared the findings with those of 15 obese patients without Cushing's syndrome. Patients with Cushing's syndrome had increased numbers of platelets, moderately elevated serum lactic dehydrogenase and gamma-glutamyltranspeptidase levels, and significantly lower creatine phosphokinase and choline esterase activities compared with those of obese control patients. We concluded that when several of these abnormal values were seen in obese patients the levels of suspicion for Cushing's syndrome should be high. |
| Databáze: | OpenAIRE |
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