Biomimetic hierarchical micro/nano texturing of TiAlV alloys by femtosecond laser processing for the control of cell adhesion and migration
| Autor: | M. Manso-Silván, Miguel Martinez-Calderon, Raúl J. Martín-Palma, Josefa P. García-Ruiz, M. Gómez-Aranzadi, Ainara Rodriguez, Santiago M. Olaizola |
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| Přispěvatelé: | UAM. Departamento de Física Aplicada, UAM. Departamento de Biología Molecular |
| Rok vydání: | 2020 |
| Předmět: |
Topography
Materials science Fabrication Physics and Astronomy (miscellaneous) Nanotechnology 02 engineering and technology Stem cells 01 natural sciences law.invention Human mesenchymal stem cells law 0103 physical sciences Nano Titanium alloys General Materials Science 010306 general physics Cell adhesion Laser processing technology industry and agriculture Titanium alloy Física 021001 nanoscience & nanotechnology Laser Femtosecond Micro nano Cell culture 0210 nano-technology |
| Zdroj: | Biblos-e Archivo. Repositorio Institucional de la UAM instname |
| Popis: | The control of the interaction between materials and biological tissues is a key factor to optimize the overall performance of implants and prostheses integrated into the body. With this objective in mind, biomimetic hierarchical one- and two-dimensional surface patterns textured at the micro and nano scales were fabricated on titanium alloys using femtosecond laser processing. The experimental results show that laser irradiation promotes surface oxidation together with a polarization-dependent nano-ripple formation. Human mesenchymal stem cells were subsequently cultured on different surface patterns aiming at determining their response to the underlying micro and nano structures. The ripple topography was demonstrated to induce a nonfouling behavior, which could be exploited in the fabrication of biomimetic hierarchical surface patterns to develop cell-trapping modules The authors are grateful for funding provided by Ministerio de Economía y Competitividad (Spain), under project reference numbers MAT2014-54826-C2-1-R and MAT2014-54826-C2-2-R and NanoNeuroDev (Grant No. 2017/EEUU/11) from Santander-Universidad |
| Databáze: | OpenAIRE |
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