Comparison between MRI with spin-echo echo-planar diffusion-weighted sequence (DWI) and histology in the diagnosis of soft-tissue tumours
| Autor: | Eugenio Annibale Genovese, Carlo Fugazzola, A. Canì, Anna Leonardi, Mg Angeretti, S. Rizzo |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Soft Tissue Neoplasms Sensitivity and Specificity Nuclear magnetic resonance medicine Humans Radiology Nuclear Medicine and imaging Neuroradiology Aged Aged 80 and over medicine.diagnostic_test business.industry Echo-Planar Imaging Ultrasound Soft tissue Magnetic resonance imaging Histology General Medicine Middle Aged Magnetic Resonance Imaging Diffusion Magnetic Resonance Imaging Spin echo Female Radiology business Echo planar |
| Popis: | Our aim was to assess the usefulness of magnetic resonance imaging (MRI) with spin-echo echo-planar diffusion-weighted sequences (SE-EPI-DWI) in the study of primary and secondary soft-tissue tumours by correlating the results of imaging and histology.We retrospectively studied 23 patients (14 men, 9 women; age range 25-87 years) affected by soft-tissue lesions. The MRI study was performed with baseline and contrast-enhanced SE-T1, proton density/T2-weighted (PD/T2), fat-saturated (FATSAT) DP/T2 and single-shot SE-EPI-DWI (b value 50-400- 800s/mm2) sequences.We identified 7/23 benign lesions (three myxoid, four nonmyxoid) and 16/23 malignant tumours (four myxoid, 12 nonmyxoid) with a mean diameter between 21 mm and 20 cm. Qualitative analysis of DWI showed persistence of high signal intensity for increasing b-values in all malignant tumours. Quantitative DWI analysis of the apparent diffusion coefficient (ADC) maps showed a statistical difference between benign and malignant lesions.In our experience, DWI with qualitative and quantitative analysis correlated well with histology. |
| Databáze: | OpenAIRE |
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