Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?
| Autor: | Bilge Karsli, Zekiye Bigat, F. Ertugrul, Demet Gulec, Nurten Kayacan |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Aging medicine.medical_specialty medicine.medical_treatment Urinary Bladder Hemodynamics Blood Pressure In Vitro Techniques Intrathecal Anesthesia Spinal Biochemistry medicine Humans Anesthetics Local Injections Spinal Aged Levobupivacaine Transurethral resection of the prostate Bupivacaine Urinary bladder business.industry Biochemistry (medical) Prostate Transurethral Resection of Prostate Nerve Block Cell Biology General Medicine Blockade Surgery medicine.anatomical_structure Blood pressure Anesthesia Female business medicine.drug |
| Zdroj: | Journal of International Medical Research. 42:376-385 |
| ISSN: | 1473-2300 0300-0605 |
| Popis: | ObjectivesTo compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged ≥65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M).MethodsPatients scheduled to undergo TUR-P or TUR-M were randomized to receive either 3 ml (15 mg) 0.5% isobaric levobupivacaine (group L) or 3 ml (15 mg) of 0.5% hyperbaric bupivacaine (group B) for spinal anaesthesia. The onset time, maximum level and time to reach the maximum level of sensory and motor blockade were recorded. Changes to haemodynamic parameters were also recorded.ResultsThe study randomized 100 patients: 57 to group L and 43 to group B. Levobupivacaine did not cause any significant changes in haemodynamic parameters, including systolic blood pressure, and showed a similar sensory block onset time compared with bupivacaine, but it had a significantly longer motor block onset time compared with bupivacaine.ConclusionThese current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥65 years of age undergoing elective TUR-P or TUR-M operations. |
| Databáze: | OpenAIRE |
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