Red blood cell transfusion in critically-ill children and its association with outcome
| Autor: | Farah Khalid, Hafsa Sohail, Parveen Usman, Anwar Ul Haque, Qalab Abbas, Shah Ali Ahmed |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Mechanical ventilation medicine.medical_specialty Hematology business.industry Critical Illness medicine.medical_treatment Medical record Infant Retrospective cohort study General Medicine Intensive Care Units Pediatric medicine.disease Respiration Artificial Sepsis Packed Red Blood Cell Transfusion Intensive care Internal medicine medicine Risk of mortality Humans Child Erythrocyte Transfusion business Retrospective Studies |
| Zdroj: | Journal of the Pakistan Medical Association. 71 |
| ISSN: | 0030-9982 |
| DOI: | 10.47391/jpma.110 |
| Popis: | Objective To determine the indications and threshold of haemoglobin levels for packed red blood cell transfusion and its association with outcomes in a paediatric intensive care setting. Methods The retrospective study was conducted in the paediatric intensive care unit of the Aga Khan University Hospital, Karachi, and comprised medical records of all inpatients with age between 1 month and 16 years who received packed red blood cell transfusions between January and December 2017. Data was retrieved from the hospital database and was analyzed using SPSS 22. Results Of the 147 subjects with a mean age of 67.89±65.8 months, 76(51.7%) were males. Mean paediatric risk of mortality score was 11.72±7.86. Major admitting diagnosis included sepsis and multiorgan dysfunction 50(34%), respiratory diseases 26(17.7%) and haematology/oncology diseases 22(15%). The indications for transfusion was low haemoglobin in 90(61.2%) patients, shock 29(19.7%) and hypoxia 28(19%). Acute transfusion reaction was observed in 1(0.7%) patient; 120(82%) required mechanical ventilation; and 94(64%) required inotropic support. Of the total, 88(59.9%) patients survived. Paediatric risk of mortality score, need for inotropic support and mechanical ventilation were associated with mortality (p Conclusions Packed red blood cell transfusion, which is frequently prescribed in intensive care settings, was not found to be associated with favourable outcome. |
| Databáze: | OpenAIRE |
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