Spasticity, dyskinesia and ataxia in cerebral palsy
| Autor: | Vincent Roelfsema, L. A. van de Pol, Oebele F. Brouwer, K. Folmer, Marina A. J. Tijssen, Agnes Elema, Hendriekje Eggink, Daan Kremer, J. F. van Hoorn, Maria Fiorella Contarino, M. E. van Egmond |
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| Přispěvatelé: | Pediatric surgery, Movement Disorder (MD) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Deep brain stimulation Ataxia medicine.medical_treatment CLASSIFICATION Cerebral palsy 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation 030225 pediatrics Spastic medicine Spasticity CHILDHOOD DYSTONIA Dystonia Rehabilitation General Medicine medicine.disease Phenotype DEFINITION Dyskinesia Pediatrics Perinatology and Child Health Physical therapy Neurology (clinical) medicine.symptom Psychology 030217 neurology & neurosurgery DEEP BRAIN-STIMULATION |
| Zdroj: | European Journal of Paediatric Neurology, 21(5), 703-706 European Journal of Paediatric Neurology, 21(5), 703-706. W.B. Saunders Ltd European Journal of Paediatric Neurology, 21(5), 703-706. ELSEVIER SCI LTD Eggink, H, Kremer, D, Brouwer, O F, Contarino, M F, van Egmond, M E, Elema, A, Folmer, K, van Hoorn, J F, van de Pol, L A, Roelfsema, V & Tijssen, M A J 2017, ' Spasticity, dyskinesia and ataxia in cerebral palsy : Are we sure we can differentiate them? ', European Journal of Paediatric Neurology, vol. 21, no. 5, pp. 703-706 . https://doi.org/10.1016/j.ejpn.2017.04.1333 |
| ISSN: | 1532-2130 1090-3798 |
| Popis: | Objective: Cerebral palsy (CP) can be classified as spastic, dyskinetic, ataxic or combined. Correct classification is essential for symptom-targeted treatment. This study aimed to investigate agreement among professionals on the phenotype of children with CP based on standardized videos.Methods: In a prospective, observational pilot study, videos of fifteen CP patients (8 boys, mean age 11 +/- 5y) were rated by three pediatric neurologists, three rehabilitation physicians and three movement disorder specialists. They scored the presence and severity of spasticity, ataxia or dyskinesias/dystonia. Inter- and intraobserver agreement were calculated using Cohen's and Fleiss' kappa.Results: We found a fair inter-observer (K = 0.36) and moderate intra-observer agreement (K = 0.51) for the predominant motor symptom. This only slightly differed within the three groups of specialists (K = 0.33-0.55).Conclusion: A large variability in the phenotyping of CP children was detected, not only between but also within clinicians, calling for a discussing on the operational definitions of spasticity, dystonia and ataxia. In addition, the low agreement found in our study questions the reliability of use of videos to measure intervention outcomes, such as deep brain stimulation in dystonic CP. Future studies should include functional domains to assess the true impact of management options in this highly challenging patient population. |
| Databáze: | OpenAIRE |
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