The Association of Age, Sex, and RT-PCR Results with the Lymphocyte and Neutrophil Counts in SARS-CoV-2 Infection: A Cross-sectional Analysis of 1450 Iranian Patients with COVID-19
| Autor: | Abdol Majid Cheraghali, Mohammad Javad Soltanpoor, Parisa Naseri, Davood Bashash, Hassan Abolghasemi, Abbas Ali Imani Fooladi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Neutrophils Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Lymphocyte Iran law.invention Sex Factors law Internal medicine medicine Humans Immunology and Allergy Lymphocyte Count Lymphocytes Polymerase chain reaction Aged Retrospective Studies business.industry SARS-CoV-2 Age Factors COVID-19 Gold standard (test) Odds ratio Middle Aged Neutrophilia Cross-Sectional Studies medicine.anatomical_structure Real-time polymerase chain reaction COVID-19 Nucleic Acid Testing RNA Viral Medicine Female medicine.symptom business |
| Zdroj: | Iranian Journal of Allergy, Asthma and Immunology, Vol 20, Iss 2 (2021) |
| ISSN: | 1735-5249 1735-1502 |
| Popis: | Containment of pandemic infections mainly depends on prompt identification of carriers, achievable through strict surveillance and truthful diagnostic testing. Although molecular identification of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the gold standard method, its low sensitivity and long turnaround time are among major concerns. In this retrospective single-center study, we reviewed the results of the lymphocyte and neutrophil counts of 1450 Iranian patients with coronavirus disease 2019 (COVID-19) recruited at Baqiyatallah Hospital, Tehran, Iran. Of 1450 patients, 439 cases (30.3%) were polymerase chain reaction (PCR) negative; further emphasizing that getting negative molecular testing is not as reliable as a positive result. While the lymphocyte count in cases with less than 50 years old was 1.8×103/µL (1.2-2.5), it was 1.47×103/µL (0.84-2.16) in the older group (p |
| Databáze: | OpenAIRE |
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