Plasma Adiponectin Concentration in Relation to Severity of Coronary Atherosclerosis and Cardiovascular Risk Factors in Middle-Aged Men
| Autor: | Katarzyna Dunajska, Karol Poczcatek, Jadwiga Szymczak, Wiktor Kuliczkowski, Piotr Salomon, Andrzej Milewicz, Przemysław Nowicki, Diana Jcedrzejuk, Dariusz Biały |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Endocrinology Diabetes and Metabolism Coronary Artery Disease Severity of Illness Index Statistics Nonparametric Body Mass Index Coronary artery disease Endocrinology Insulin resistance Reference Values Risk Factors Internal medicine Diabetes mellitus medicine Humans Testosterone Coronary atherosclerosis Analysis of Variance Estradiol medicine.diagnostic_test Adiponectin business.industry Cholesterol HDL Quantitative insulin sensitivity check index nutritional and metabolic diseases Middle Aged medicine.disease Coronary arteries medicine.anatomical_structure Intercellular Signaling Peptides and Proteins Insulin Resistance business Lipid profile hormones hormone substitutes and hormone antagonists |
| Zdroj: | Endocrine. 25:215-222 |
| ISSN: | 0969-711X |
| DOI: | 10.1385/endo:25:3:215 |
| Popis: | Adiponectin, an adipocyte-derived protein, seems to be a link between obesity, insulin resistance, and atherosclerosis. The present study investigated the association between adiponectin and coronary artery disease in middle-aged men. Material and methods: We examined 48 men (aged 40–60) with angiographically confirmed coronary atherosclerosis and 19 healthy men, matched by age, as a control group. Concentrations of glucose and lipids were estimated with enzymatic methods. Plasma level of adiponectin, total and free testosterone, estradiol, estrone, DHEA-S, and insulin were estimated with RIA commercial kits. Results: Men with coronary atherosclerosis had lower plasma adiponectin level than controls (16.2±9.2 vs 20.5±6.7 µg/mL; p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink