PREDISPOSING FACTORS AND AETIOLOGY OF URINARY TRACT INFECTIONS IN PREGNANT WOMEN
| Autor: | Mahendra Sharma, Agrima Darbari, Ved Prakash, Lata Agarwal, H. K. Premi, Prem Prakash Mishra, Hlufong Mog, Sumit Agarwal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Escherichia Coli 030219 obstetrics & reproductive medicine business.industry lcsh:R5-130.5 Urinary system UTI Sensitivity bacterial infections and mycoses Multiparity 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine medicine Etiology 030212 general & internal medicine business lcsh:General works |
| Zdroj: | Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 45, Pp 2244-2248 (2016) |
| ISSN: | 2349-2570 2349-2562 |
| Popis: | BACKGROUND Urinary tract infection (UTI) is a common infection in pregnant women. It is responsible for range of complications causing perinatal and maternal morbidity and mortality. AIM To assess the associated risk factors, aetiology and their antibiogram of UTI among pregnant women. METHODOLOGY This is a cross-sectional study carried out in Department of Microbiology & Department of Obstetrics from March 2015 to February 2016. The patient details and risk factors were recorded. Midstream & catheter urine specimens from pregnant women with symptoms of UTI were collected and sent for routine microscopy, culture and sensitivity. RESULTS In 550 pregnant women, 122(22.18%) had significant bacteriuria and 72(17.72%) had low colony count UTI. The most affected number age group was 25-35 years (58.85%) followed by 15-25 years. Of the associated risk factors, multiparity 45.31%, low socioeconomic status 42.18%, anaemia 39.06% etc. were important. Escherichia coli was most frequently isolated with a percentage of 29.14%, followed by Klebsiella species (17.49%), S. aureus (14.34%) etc. Other isolated micro-organisms included Enterococci, Proteus mirabilis, Citrobacter, Pseudomonas, Acinetobacter species. The antibiotics with more than 50% sensitivity against Gram-negative isolates were Imipenem (74.7%), Levofloxacin (73.17%), Ciprofloxacin (69.10%), Amikacin (57.72%), Amoxiclav (55.28%), and Cefoperazone/Sulbactam (50.40%). The antibiotics for Gram-positive isolates were Linezolid (88.46%), Cefoxitin (78.84%), Teicoplanin (69.23%) and Vancomycin (65.22%). CONCLUSION We found associated risk factors such as multiparity, low socioeconomic status, etc. E. coli was the most common bacteria isolated in our setting. Therefore, pregnant women should be assessed for associated risk factors and evaluated for the pathogenic organism during their regular follow-up. The drug sensitivity should be taken into consideration with their side effects related to pregnancy. |
| Databáze: | OpenAIRE |
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