Author Correction: Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life
| Autor: | Mei Ling J N Chu, Susana Fuentes, Elisabeth A. M. Sanders, Wing Ho Man, Astrid A. T. M. Bosch, Debbie van Baarle, Marta Reyman, Marlies A. van Houten, Rebecca L. Watson, Kayleigh Arp, Debby Bogaert |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
DNA
Bacterial 0301 basic medicine Science Population Dynamics General Physics and Astronomy First year of life 02 engineering and technology Computational biology Biology Gut flora Paediatric research General Biochemistry Genetics and Molecular Biology Feces 03 medical and health sciences Pregnancy RNA Ribosomal 16S Humans Author Correction lcsh:Science Multidisciplinary Bacteria Cesarean Section Shotgun sequencing Infant Newborn Infant Sequence Analysis DNA General Chemistry Delivery Obstetric 021001 nanoscience & nanotechnology biology.organism_classification Delivery mode Gastrointestinal Microbiome 030104 developmental biology Vagina Infectious diseases Female lcsh:Q Microbiome 0210 nano-technology |
| Zdroj: | Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019) Nature Communications |
| ISSN: | 2041-1723 |
| Popis: | The early-life microbiome appears to be affected by mode of delivery, but this effect may depend on intrapartum antibiotic exposure. Here, we assess the effect of delivery mode on gut microbiota, independent of intrapartum antibiotics, by postponing routine antibiotic administration to mothers until after cord clamping in 74 vaginally delivered and 46 caesarean section born infants. The microbiota differs between caesarean section born and vaginally delivered infants over the first year of life, showing enrichment of Bifidobacterium spp., and reduction of Enterococcus and Klebsiella spp. in vaginally delivered infants. The microbiota composition at one week of life is associated with the number of respiratory infections over the first year. The taxa driving this association are more abundant in caesarean section born children, providing a possible link between mode of delivery and susceptibility to infectious outcomes. |
| Databáze: | OpenAIRE |
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