Simplification of Antiretroviral Therapy to a Single-Tablet Regimen Consisting of Efavirenz, Emtricitabine, and Tenofovir Disoproxil Fumarate Versus Unmodified Antiretroviral Therapy in Virologically Suppressed HIV-1-Infected Patients

Autor:	Ramin Ebrahimi, John F. Flaherty, Douglas J. Ward, Awny Farajallah, Damian J McColl, Javier O Morales-Ramirez, Karen Reilly, Daniel Seekins, Benjamin Young, Edwin DeJesus, Louis Sloan, Janet Ecker, Jen-Fue Maa
Rok vydání:	2009
Předmět:	Adult Cyclopropanes Male medicine.medical_specialty Efavirenz Anti-HIV Agents Organophosphonates HIV Infections Emtricitabine Deoxycytidine Gastroenterology chemistry.chemical_compound Internal medicine medicine Humans Pharmacology (medical) Tenofovir Intention-to-treat analysis Reverse-transcriptase inhibitor business.industry Adenine Liter Middle Aged Confidence interval Benzoxazines Surgery Discontinuation Drug Combinations Regimen Infectious Diseases chemistry Alkynes HIV-1 Patient Compliance Female business medicine.drug
Zdroj:	JAIDS Journal of Acquired Immune Deficiency Syndromes. 51:163-174
ISSN:	1525-4135
DOI:	10.1097/qai.0b013e3181a572cf
Popis:	Objective: To evaluate a simplification strategy for HIV-1―infected patients virologically suppressed on antiretroviral therapy (ART) by switching to a single-tablet regimen consisting of efavirenz/ emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF). Design: Prospective, randomized, controlled, open-label, multicenter study. Methods: Patients on stable ART with HIV-1 RNA
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b91c04c23ba47dbe9a3c770d88355b0 https://doi.org/10.1097/qai.0b013e3181a572cf Zobrazit plný text záznamu