The Diagnostic Value of Cervical Lymph Node Metastasis in Head and Neck Squamous Carcinoma by Using Diffusion-Weighted Magnetic Resonance Imaging and Computed Tomography Perfusion
| Autor: | Yi Gong, Xuehuan Liu, Zhenxing Liu, Caixian Hao, Li He, Liang Xu, Rui Hua, Changqing Zong, Jun Liu, Hui Qiao, Longchun Dong, Jin Zhong, Zonghong Lu |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Article Subject lcsh:Medicine General Biochemistry Genetics and Molecular Biology Carcinoma Medicine Effective diffusion coefficient Humans Aged General Immunology and Microbiology medicine.diagnostic_test business.industry Squamous Cell Carcinoma of Head and Neck lcsh:R Magnetic resonance imaging General Medicine Middle Aged medicine.disease Head and neck squamous-cell carcinoma Squamous carcinoma Perfusion medicine.anatomical_structure Diffusion Magnetic Resonance Imaging Head and Neck Neoplasms Lymphatic Metastasis Clinical Study Carcinoma Squamous Cell Cervical Vertebrae Female Lymph Radiology business Tomography X-Ray Computed Cervical vertebrae |
| Zdroj: | BioMed Research International BioMed Research International, Vol 2014 (2014) |
| ISSN: | 2314-6133 |
| DOI: | 10.1155/2014/260859 |
| Popis: | Purpose.The aim of this study was to compare diffusion-weighted magnetic resonance imaging (DWI) with computed tomography perfusion (CTP) for preoperative detection of metastases to lymph nodes (LNs) in head and neck squamous cell carcinoma (SCC).Methods.Between May 2010 and April 2012, 30 patients with head and neck SCC underwent preoperative DWI and CTP. Two radiologists measured apparent diffusion coefficient (ADC) values and CTP parameters independently. Surgery and histopathologic examinations were performed on all patients.Results.On DWI, 65 LNs were detected in 30 patients. The mean ADC value of metastatic nodes was lower than benign nodes and the difference was statistically significant (P<0.05). On CTP images, the mean value in metastatic nodes of blood flow (BF) and blood volume (BV) was higher than that in benign nodes, and mean transit time (MTT) in metastatic nodes was lower than that in benign nodes. There were significant differences in BF and MTT values between metastatic and benign LNs (P<0.05). There were significant differences between the AUCs of DWI and CTP (Z=4.612,P<0.001).Conclusion.DWI with ADC value measurements may be more accurate than CTP for the preoperative diagnosis of cervical LN metastases. |
| Databáze: | OpenAIRE |
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