Can bone wax cause cholesterol granuloma in the petrous apex? A case report

Autor: Prepageran Narayanan, Eugene Hung Chih Wong, Chee Chean Lim, Cheng Ai Ong
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Surgery Case Reports
ISSN: 2210-2612
Popis: Highlights • Bone wax, due to its non-resorbable property is known to cause foreign body reaction. • Cholesterol granuloma can possibly manifest as a complication of bone wax usage from previous surgeries. • Surgical excision of the cholesterol granuloma with removal of its inciting agent is one of the management options. • More studies should be conducted with regards to bone wax causing cholesterol granuloma in the petrous apex as this is the first case described in the literature. • Surgeons should be aware of this potential complication and use hemostatic agents, in particular bone wax more judiciously.
Background Cholesterol granuloma (CG) is a rare entity but is the commonest lesion in the petrous apex. They are associated with chronic ear disease and previous temporal bone surgery. While bone wax has been known to cause foreign body reaction due to its non-resorbable property in the mastoid, it has not been documented to cause CG formation. Case presentation We described a 43 years old male who presented with a right mastoid swelling, nine years after a right retro-sigmoid craniotomy and excision for a cerebellopontine angle meningioma. He also had multiple cranial neuropathies involving trigeminal, facial and vestibulocochlear nerves. Temporal bone CT and MRI showed features suggestive of cholesterol granuloma with extensive bony erosions. He was treated with surgical excision and drainage where bone wax residues were found intraoperatively. Histopathological analysis of the lesion confirmed the diagnosis of cholesterol granuloma. Post-operatively, the mastoid swelling resolved and his recovery was uneventful. Conclusion Our case showed that CG could manifest as a complication of bone wax usage in a neurosurgical procedure. Even though further study is needed to draw a definitive conclusion on this theory, we believe this paper will contribute to the current literature as it is the only reported case of cholesterol granuloma with bone wax as the possible causative agent. This is important so that surgeons are aware of this potential complication and use this haemostatic agent more judiciously.
Databáze: OpenAIRE