Modeling drug exposure in rodents using e-cigarettes and other electronic nicotine delivery systems
| Autor: | Emma R. Gnatowski, Malissa M. Reyes, Matthew W. Buczynski, E. Reilly Scott, Laura B. Murdaugh, Cristina Miliano, Megan S. Anderson, Christine L. Faunce, Ann M. Gregus |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Drug medicine.medical_specialty Drugs of abuse Nicotine media_common.quotation_subject Rodentia Electronic Nicotine Delivery Systems Article 03 medical and health sciences Preclinical research 0302 clinical medicine Cigarette smoking medicine Animals Preventable death Intensive care medicine media_common business.industry General Neuroscience Smoking Tobacco Vaping Peripheral Nervous System Agents Rats Disease Models Animal 030104 developmental biology Nicotine delivery Central Nervous System Stimulants business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | J Neurosci Methods |
| ISSN: | 1872-678X |
| Popis: | Smoking tobacco products is the leading cause of preventable death worldwide. Coordinated efforts have successfully reduced tobacco cigarette smoking in the United States; however, electronic cigarettes (e-cigarette) and other electronic nicotine delivery systems (ENDS) recently have replaced traditional cigarettes for many users. While the clinical risks associated with long-term ENDS use remain unclear, advancements in preclinical rodent models will enhance our understanding of their overall health effects. This review examines the peripheral and central effects of ENDS-mediated exposure to nicotine and other drugs of abuse in rodents and evaluates current techniques for implementing ENDS in preclinical research. |
| Databáze: | OpenAIRE |
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