Platelet factor 3 in Glanzmann's thrombasthenia
| Autor: | Ram Kishan, Jaya Kasturi, A.K. Saraya |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Adult
Blood Platelets Male congenital hereditary and neonatal diseases and abnormalities Adolescent Lipoproteins Clot retraction Platelet Adhesiveness Thrombasthenia Bleeding time hemic and lymphatic diseases Platelet adhesiveness medicine Humans Platelet activation Blood Platelet Disorders Aged medicine.diagnostic_test Glanzmann's thrombasthenia business.industry Venoms Platelet Factor 3 Hematology General Medicine Syndrome Middle Aged medicine.disease Blood Coagulation Factors Purpura Thrombocytopenic Immunology Female Blood Coagulation Tests business |
| Zdroj: | Acta haematologica. 48(2) |
| ISSN: | 0001-5792 |
| Popis: | The present paper describes 3 cases of classical thrombasthenia and 3 cases of combined platelet factor 3 defi- 3 ciency and absence of platelet aggregation. The bleeding time and the clot retraction in the latter 3 patients were They, however, did not differ in clinical presentation of classical thrombasthenia. These cases have been designated as thrombopathic thrombasthenia. The possibility of an in vivo platelet activation leading to variable amounts of platelet factor 3 release in thrombasthenia has been raised. Mechanism of PF3 release in vivo in thrombasthenia, however, is not known and needs further study. |
| Databáze: | OpenAIRE |
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