Serum 25-OH vitamin D levels in systemic sclerosis: analysis of 140 patients and review of the literature

Autor:	Carlo Umberto Manzini, Michele Colaci, Dilia Giuggioli, Federica Lumetti, Giulia Cassone, Andrea Antonelli, Andreina Teresa Manfredi, Federica Campomori, Clodoveo Ferri, Amelia Spinella, P Fallahi
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	0301 basic medicine Male Adult medicine.medical_specialty Parathyroid hormone Autoimmunity Gastroenterology vitamin D deficiency Group B Scleroderma Autoimmune thyroiditis 03 medical and health sciences 0302 clinical medicine Rheumatology Calcinosis Internal medicine medicine Vitamin D and neurology Humans Vitamin D Hypovitaminosis D Systemic sclerosis Aged 030203 arthritis & rheumatology Female Middle Aged Parathyroid Hormone Scleroderma Systemic Vitamin D Deficiency Systemic business.industry General Medicine medicine.disease 030104 developmental biology Endocrinology business
Popis:	Hypovitaminosis D is increasingly reported in autoimmune diseases. We investigated the 25-OH-vitamin D (25-OH-vitD) levels in systemic sclerosis (SSc) patients, in correlation with disease’s features. We measured the 25-OH-vitD serum levels in 140 consecutive patients (F/M 126/15; mean age 61 ± 15.1 years), 91 without (group A) and 49 with (group B) 25-OH-cholecalciferol supplementation. Patients of group A invariably showed low 25-OH-vitD levels (9.8 ± 4.1 ng/ml vs. 26 ± 8.1 ng/ml of group B); in particular, 88/91 (97%) patients showed vitamin D deficiency (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b6685ca0b693ebaa68a065e6003b2bb http://hdl.handle.net/20.500.11769/322064 Zobrazit plný text záznamu