The role of progesterone elevation in IVF
| Autor: | Nicola Pluchino, Panagiotis Drakopoulos, Joaquín Errázuriz, Herman Tournaye, Christophe Blockeel, Michel De Vos, Annalisa Racca, Samuel Santos-Ribeiro |
|---|---|
| Přispěvatelé: | Surgical clinical sciences, Centre for Reproductive Medicine - Gynaecology, Follicle Biology, Biology of the Testis, Reproduction and Genetics, Faculty of Medicine and Pharmacy |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
endometrial receptivity medicine.medical_treatment Fertilization in Vitro Cryopreservation Andrology 03 medical and health sciences endocrinology 0302 clinical medicine Human fertilization Progesterone/blood Pregnancy Follicular phase medicine Humans Progesterone elevation implantation Progesterone ddc:618 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Mammalian Pregnancy Outcome Embryo Embryo Mammalian Institutional repository 030104 developmental biology embryo quality Female Animal Science and Zoology Endometrial receptivity business in vitro fertilization Embryo quality Developmental Biology |
| Zdroj: | Reproductive Biology, Vol. 19, No 1 (2019) pp. 1-5 |
| ISSN: | 1642-431X |
| DOI: | 10.1016/j.repbio.2019.02.003 |
| Popis: | Elevation of progesterone during the late follicular phase of stimulated in-vitro fertilization cycles is a frequent event, which negatively impacts the outcome. Over the years evidence has demonstrated a direct relationship between late-follicular elevated progesterone and endometrial receptivity. In this regard, elective cryopreservation of all good quality embryos and transfer in a subsequent frozen/thawed cycle is the most common strategy adopted by clinicians in case of elevated progesterone. Nonetheless, recent evidence suggests that elective cryopreservation might not entirely resolve the reduced pregnancy outcomes associated with the elevation of progesterone, considering that the increase may affect not only implantation, but also embryo quality. |
| Databáze: | OpenAIRE |
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